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KMID : 0644120110240040095
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Journal of Oriental Gynecology
2011 Volume.24 No. 4 p.95 ~ p.104
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A Study of the Relationship between the Degree of Menopausal Symptom and Granulocyte/Lymphocyte Ratio, Heart Rate Variability in Some Perimenopausal Women
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Heo Su-Jeong
Lee Jin-Moo
Lee Chang-Hoon
Lee Kyung-Sub
Jang Jun-Bock
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Abstract
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Objectives: The purpose of this study is to investigate the relationship between the degree of menopausal symptom and granulocyte/lymphocyte ratio, and heart rate varibility(HRV).
Methods: From 11th April 2011 to 20th May 2011, a total 30 female subjects (age 41-60) was recruited. We evaluated the degree of menopausal symptoms by Kupperman’ s index and measured subject’s WBC differential count and HRV. The data were analyzed by Kruskal-Wallis test and Spearman correlation test using SPSS/PC ver 13.0 program.
Results: 1. There was no statistically significant difference in granulocyte/lymphocyte ratio and HRV among 4 classified groups according to Kupperman’s index.- Mild, Moderate, Severe and Urgent. 2. Granulocyte ratio and general symptom score(within Kupperman’s index) significantly showed negative correlation coefficient(r=-0.499, p=0.005), and Lymphocyte ratio and general symptom score significantly showed positive correlation coefficient (r=0.374, p=0.042). 3. Granulocyte/lymphocyte ratio and HRV showed no significant correlation.
Conclusions: There was no significant relation among the degree of menopausal symptoms and granulocyte/lymphocyte ratio, and HRV. But furthermore large scale study is required.
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KEYWORD
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Menopausal syndrome, Granulocyte/Lymphocyte ratio, HRV, Kupperman’s index
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